Iburpofen, how many how long?
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Iburpofen, how many how long?
hi all,
i am wondering how long it is safe to stay on ibuprofen? I have been taking one a day for months now. It helps curb the inflammation and pain I am still having in the anal area. Any sage owrds of advice?
i am wondering how long it is safe to stay on ibuprofen? I have been taking one a day for months now. It helps curb the inflammation and pain I am still having in the anal area. Any sage owrds of advice?

buttgirl- Moderator

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Number of posts: 1446
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Re: Iburpofen, how many how long?
I am all out of sage words of advice but to me 1 advil a day doesn't sound problematic. I took 8 advil a day for a month and have used painkillers on and off at different levels due to chronic pain. For me I have just decided I have to absorb some of the risk so I can have some level of normalcy in my life.
I think as long as you take it with food there ought not to be a problem!
I think as long as you take it with food there ought not to be a problem!

Tootie- Admin

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Number of posts: 7177
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Re: Iburpofen, how many how long?
At just one or two a day, it appears from what I can google, that Chris is fine. But in Lecia's case it is much more difficult to judge. I would beg Lecia to not take it month after month at such a high dose, and it appears from her reply above that she doesn't. It can eventually damage the kidney(s)after long-term high dose usage.
http://209.85.165.104/search?q=cache:aJLoQpNFB2AJ:answers.cbfl.net/answers/threadview%3Fid%3D72200+long-term+use+of+ibuprofen&hl=en&ct=clnk&cd=8&gl=us
Kidney Effects: As with other nonsteroidal anti-inflammatory drugs,
long-term administration of ibuprofen to animals has resulted in renal
papillary necrosis and other abnormal renal pathology. In humans,
there have been reports of acute interstitial nephritis with
hematuria, proteinuria, and occasionally nephrotic syndrome.. A second
form of renal toxicity has been seen in patients with prerenal
conditions leading to a reduction in renal blood wflow or blood
volume, where the renal prostaglandins have a supportive role in the
maintenance of renal perfusion... …Those patients at high risk who
chronically take ibuprofen should have renal function monitored if
they have signs or symptoms which may be consistent with mild
azotemia, such as malaise, fatigue, loss of appetite, etc. Occasional
patients may develop some elevation of serum creatinine and BUN levels
without signs or symptoms.”
I hope this helps
http://209.85.165.104/search?q=cache:aJLoQpNFB2AJ:answers.cbfl.net/answers/threadview%3Fid%3D72200+long-term+use+of+ibuprofen&hl=en&ct=clnk&cd=8&gl=us
Kidney Effects: As with other nonsteroidal anti-inflammatory drugs,
long-term administration of ibuprofen to animals has resulted in renal
papillary necrosis and other abnormal renal pathology. In humans,
there have been reports of acute interstitial nephritis with
hematuria, proteinuria, and occasionally nephrotic syndrome.. A second
form of renal toxicity has been seen in patients with prerenal
conditions leading to a reduction in renal blood wflow or blood
volume, where the renal prostaglandins have a supportive role in the
maintenance of renal perfusion... …Those patients at high risk who
chronically take ibuprofen should have renal function monitored if
they have signs or symptoms which may be consistent with mild
azotemia, such as malaise, fatigue, loss of appetite, etc. Occasional
patients may develop some elevation of serum creatinine and BUN levels
without signs or symptoms.”
I hope this helps

Kim- Admin

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Number of posts: 7043
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Re: Iburpofen, how many how long?
Thanks Kim and Lecia. I appreciate the input. It's so nice to have people to bounce ideas and concerns off of.

buttgirl- Moderator

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Re: Iburpofen, how many how long?
Hello,
I have been taking Advil on and off since June. I take it with food and I drink alot of water. I take it with extreme pain. It is only when you take it for a long time it could cause damage to you kidneys and liver. I am going to ask my doctor what he thinks.
Patty
:snn:
I have been taking Advil on and off since June. I take it with food and I drink alot of water. I take it with extreme pain. It is only when you take it for a long time it could cause damage to you kidneys and liver. I am going to ask my doctor what he thinks.
Patty
:snn:
Guest- Guest
Re: Iburpofen, how many how long?
Thanks, Patty. Ask him if taking 800 mg at a time for over a month is serioous...

Kim- Admin

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Number of posts: 7043
Registration date: 2006-11-07
Re: Iburpofen, how many how long?
My doctor told me I could!

Tootie- Admin

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Number of posts: 7177
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Re: Iburpofen, how many how long?
I sometimes take high doses when I have back trouble, so I was wondering.

Kim- Admin

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Number of posts: 7043
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Re: Iburpofen, how many how long?
Ibuprofen has the lowest risk of gastrointestinal effects
http://www.jr2.ox.ac.uk/bandolier/booth/painpag/nsae/nsae.html
Here is some info on gastrointestinal and renal toxicity of Ibuprofen:
http://www.fda.gov/ohrms/dockets/ac/02/briefing/3882B2_06_International%20Ibuprofen%20Foundation.htm
http://www.jr2.ox.ac.uk/bandolier/booth/painpag/nsae/nsae.html
Here is some info on gastrointestinal and renal toxicity of Ibuprofen:
http://www.fda.gov/ohrms/dockets/ac/02/briefing/3882B2_06_International%20Ibuprofen%20Foundation.htm
Christine- Fibre Addict
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Re: Iburpofen, how many how long?
Thanks for the links! I can tell you have done a lot of your own research.

Tootie- Admin

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Re: Iburpofen, how many how long?
i've taken 800mg of ibuprofen almost every day for about 4 months now. it at least helps me not to constantly think about the fissure. i'm slowly trying to cut back, as i'm HOPING my fissure is healing and i won't need it as much. the past 2 days i've only taken 400mg.
my surgeon told me it was ok to take 800mg everyday for awhile as i'm healing, but another dr seemed concerned with taking that much everyday. who knows? i don't even think the dr's have a clear idea. i think anything that helps you get thru the day (and your life!) should be used. i know there are some days i absolutely couldn't live without a mild painkiller.
my surgeon told me it was ok to take 800mg everyday for awhile as i'm healing, but another dr seemed concerned with taking that much everyday. who knows? i don't even think the dr's have a clear idea. i think anything that helps you get thru the day (and your life!) should be used. i know there are some days i absolutely couldn't live without a mild painkiller.
juney- Moderator

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Re: Iburpofen, how many how long?
Ibuprofen makes my stomach go crazy - I mean I get diarrhea INSTANTLY : (. I also can't take Alive and such. So, I asked 3 days ago for Relafen, (Nabutamene sp?), which is NSAID that I took for 2 years while I had Fibro. It does, as all NSAIDs effects liver and kidneys and can cause internal bleeding, but with this one (since it is by prescription only) they have to check your liver function every 3 months and urine too - so there is no guessing ; ). I decided to try to take it to curb my inflamation around the fissure site which is always present with every fissure. This drug , plus those 2 creams and Valium are my last attempt to get rid of this nightmare - 4 weeks more and I am going for LIS! Last day I felt somewhat better, ahhhhhhhhhh what a relief when sphincter "lets go" , oh my gosh, it is like a night and day !!!!! At least now I am sure that nothing else is causing my pain but stupid muscle, oh sometimes when I chop vegetables I have an urge to snap it myself ; )!!! My older daughter is very worried about me, just can't stand seeing me cry occasionally, so in full frustration she was wondering aloud: " I wonder what cave man did in hose situation???" " Nothing", I said, " They just couldn't run fast enough and cyber tiger just got them and saved them from further suffering "!!! We both laughed so much : )))... Anybody has a pet tiger, perhaps ???? ; )))

Fissulyna- VIP

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Re: Iburpofen, how many how long?
I think ibuprofen makes my kidneys go haywire! I took some the other night and my bladder filled over and over! I dehydrated pretty badly!
OK, Fissulyna, watch it with that knife, now!!
OK, Fissulyna, watch it with that knife, now!!

Kim- Admin

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Number of posts: 7043
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Re: Iburpofen, how many how long?
heh heh ; ))))) ! WHAT !!! Maybe I will find some new "do it yourself" home remedy ; ))) and strat selling it in a kit , ahhahahah. Stake knife looks pretty "dainty". Not to mention that during my Biology studies I was the best in any dissection procedure - did some procedures that other students were not able to do in 10 years in Animal Physiology Lab (very proudly said Fissulyna ; ). AND, If I look into my garage long enough I am sure I have my dissection set still there somewhere collecting the dust ; )))) ! HAH, like making a notch in the muscle is brain surgery ; )))) !!!!
LOVE this new format of the forum : ))))))!!!!!! V_E_R_Y cooooool !
LOVE this new format of the forum : ))))))!!!!!! V_E_R_Y cooooool !

Fissulyna- VIP

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Re: Iburpofen, how many how long?
I have seriously been in such pain that I have been tempted to pull a do it yourselfer on my butt. It can be that aggravating!

Tootie- Admin

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